*Note: For the investigational use of Adipose Tissue for clinical research and deployment.

5126343Crohn’s disease is a type of inflammatory bowel disease that occurs in approximately half a million people in North America. It can affect any part of the gastrointestinal tract from the mouth to the anus, causing a wide variety of symptoms, including abdominal pain, bloating, diarrhea (which may be bloody if inflammation is at its worst), vomiting (can be continuous), or weight loss. Skin rashes and arthritis can also occur. Crohn’s disease has a genetic component, but it is an auto-immune disease in which the person’s own immune system attacks the gastrointestinal tract possibly directed at microbial antigens. The terminal ileum is the part of the bowel most often affected in this disease.

Treatment often includes immunnosuppressive therapy with steroids. Antibiotics and anti-inflammatories are also used extensively. In Europe, cells derived from adipose tissue are commonly used to treat Crohn’s. Research is ongoing to evaluate the effects of these cells on autoimmune conditions.


Dr. Todd Malan has remained in the forefront of developing innovative therapies for use in treating autoimmune disease, including Crohn’s Disease. These therapies focus on repairing tissue damage as a result of both chronic disease and the use of steroid-based medications for treatment. Successful treatment can provide symptom relief and remission for improved quality of life.

The entire cellular surgical procedure takes approximately three hours.